Uniparental disomy (UPD) refers to the situation in which both copies of a chromosome pair
have originated from one parent. In humans, it can result in clinical conditions by producing …

From 11 studies, a total of 1,792 Caucasian probands with insulin-dependent diabetes
mellitus (IDDM) are analyzed. Antigen genotype frequencies in patients, transmission from …

X chromosome (X) inactivation is a remarkable biological process including the choice and
cis‐limited inactivation of one X, as well as the stable maintenance of this silencing by …

Background— The majority of infrarenal abdominal aortic aneurysm (AAA) repairs in the
United States are performed with endovascular methods. Baseline aortoiliac arterial anatomic …

BACKGROUND: Reproductive loss carries immeasurable human costs as well as being
costly to the health care system. The objectives of this study were to determine the frequency …

Background Measurement of genome-wide DNA methylation (DNAm) has become an important
avenue for investigating potential physiologically-relevant epigenetic changes. Illumina …

Tissue-specific DNA methylation is found at promoters, enhancers, and CpG islands but
also over larger genomic regions. In most human tissues, the vast majority of the genome is …

OBJECTIVE: Female fertility declines with age; however, women are increasingly delaying
childbearing until later in their reproductive years. One of the factors that may contribute to …

Maternal uniparental disomy for the entire chromosome 7 has so far been reported in three
patients with intrauterine and postnatal growth retardation. Two were detected because they …

Preeclampsia and intrauterine growth restriction (IUGR) are two of the most common adverse
pregnancy outcomes, but their underlying causes are mostly unknown. Although multiple …