Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment

SK Hobbs, WL Monsky, F Yuan… - Proceedings of the …, 1998 - National Acad Sciences
Novel anti-neoplastic agents such as gene targeting vectors and encapsulated carriers are
quite large (approximately 100–300 nm in diameter). An understanding of the functional size …

[HTML][HTML] Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice

…, P Velasco, L Richard, D Fukumura, W Monsky… - Journal of Investigative …, 1998 - Elsevier
Vascular endothelial growth factor (VEGF) has been implicated in the pathologic
angiogenesis observed in psoriasis and other chronic inflammatory skin diseases that are …

Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor

WL Monsky, D Fukumura, T Gohongi, M Ancukiewcz… - Cancer Research, 1999 - AACR
The goal of this investigation was to measure changes in vascular permeability, pore cutoff
size, and number of transvascular transport pathways as a function of time and in response to …

A potential marker protease of invasiveness, separase, is localized on invadopodia of human malignant melanoma cells

WL Monsky, CY Lin, A Aoyama, T Kelly, SK Akiyama… - Cancer research, 1994 - AACR
Seprase, a large, gelatin-degrading membrane-protease complex, is expressed at the invasive
front of malignant melanoma cells on invadopodia, and its surface expression contributes …

Contrast-enhanced dedicated breast CT: initial clinical experience

…, S Ray, SY Huang, LA Beckett, WL Monsky… - Radiology, 2010 - pubs.rsna.org
Purpose To quantify contrast material enhancement of breast lesions scanned with
dedicated breast computed tomography (CT) and to compare their conspicuity with that at …

Contrast-enhanced US for the interventional radiologist: current and emerging applications

CD Malone, DT Fetzer, WL Monsky, M Itani… - Radiographics, 2020 - pubs.rsna.org
US is a powerful and nearly ubiquitous tool in the practice of interventional radiology. Use of
contrast-enhanced US (CEUS) has gained traction in diagnostic imaging given the recent …

Effect of host microenvironment on the microcirculation of human colon adenocarcinoma.

D Fukumura, F Yuan, WL Monsky, Y Chen… - The American journal …, 1997 - ncbi.nlm.nih.gov
It is generally accepted that the host microenvironment influences tumor biology. There are
discrepancies in growth rate, metastatic potential, and efficacy of systemic treatment between …

Role of Host Microenvironment in Angiogenesis and Microvascular Functions in Human Breast Cancer Xenografts: Mammary Fat Pad versus Cranial Tumors

WL Monsky, CM Carreira, Y Tsuzuki, T Gohongi… - Clinical Cancer …, 2002 - AACR
Purpose: The host microenvironment differs between primaryand metastatic sites, affecting
gene expression and variousphysiological functions. Here we show the differencesin the …

Radiofrequency ablation of hepatic tumors: increased tumor destruction with adjuvant liposomal doxorubicin therapy

…, JB Kruskal, K Reynolds, WL Monsky… - American Journal of …, 2002 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to determine whether the administration of
liposomal doxorubicin before radiofrequency ablation increases coagulation more than …

[HTML][HTML] Radiographic and histologic response to neoadjuvant radiotherapy in patients with soft tissue sarcoma

…, M Wilton, CS Li, J Ryu, W Mak, WL Monsky… - Annals of surgical …, 2010 - Springer
Background Limited data exist regarding the radiographic and histologic response of soft
tissue sarcoma (STS) to neoadjuvant radiotherapy (RT). Methods Between February 2000 and …