Myosin VI (MVI) has been found to be overexpressed in ovarian, breast and prostate cancers.
Moreover, it has been shown to play a role in regulating cell proliferation and migration, …

During transcription, RNA Polymerase II (RNAPII) is spatially organised within the nucleus
into clusters that correlate with transcription activity. While this is a hallmark of genome …

During growth, differentiation and migration of cells, the nucleus changes size and shape,
while encountering forces generated by the cell itself and its environment. Although there is …

… Zubair Cheema and Yukti Hari-Gupta contributed equally to this work. … mechanisms of
transcriptional regulation of the AR gene by BORIS (Y. Hari-Gupta, manuscript in preparation). …

Myosin VI is involved in many cellular processes ranging from endocytosis to transcription.
This multifunctional potential is achieved through alternative isoform splicing and through …

Nuclear myosin VI (MVI) enhances RNA polymerase II – dependent transcription, but the
molecular mechanism is unclear. We used live cell single molecule tracking to follow individual …

During transcription, RNA Polymerase II (RNAPII) is spatially organised within the nucleus
into clusters that correlate with transcription activity. While this is a hallmark of genome …

Myosin VI is the only minus-end actin motor and it is coupled to various cellular processes
ranging from endocytosis to transcription. This multi-potent nature is achieved through …

… (1) L a b e l l i n g e f f i c i e n c y = A x ε × M W o f p r o t e i n m g p r o t e i n / m L = m o l
e s o f d y e m o l e s o f p r o t e i n where A x is the absorbance value of the dye at the …

NDP52 is an autophagy receptor involved in the recognition and degradation of invading
pathogens and damaged organelles. Although NDP52 was first identified in the nucleus and is …