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mTORC1-mediated inhibition of 4EBP1 is essential for Hedgehog (HH) signaling and can be targeted to suppress HH-driven medulloblastoma
Chang-Chih Wu, Shirui Hou, Brent A. Orr, Yong Ha Youn, Fanny Roth, Charles G. Eberhart, Young-Goo Han
doi: https://doi.org/10.1101/130872
Chang-Chih Wu
1Department of Developmental Neurobiology, 262 Danny Thomas Place, Memphis, TN 38105, USA
Shirui Hou
1Department of Developmental Neurobiology, 262 Danny Thomas Place, Memphis, TN 38105, USA
Brent A. Orr
2Department of Pathology, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA
Yong Ha Youn
1Department of Developmental Neurobiology, 262 Danny Thomas Place, Memphis, TN 38105, USA
Fanny Roth
3Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche en Myologie (CRM), GH Pitié Salpêtrière, 47 bld de l’hôpital, Paris 13, France
Charles G. Eberhart
4Department of Pathology, The Johns Hopkins University School of Medicine, Ross Building 558, 720 Rutland Ave, Baltimore, MD 21205, USA
Young-Goo Han
1Department of Developmental Neurobiology, 262 Danny Thomas Place, Memphis, TN 38105, USA
Article usage
Posted April 25, 2017.
mTORC1-mediated inhibition of 4EBP1 is essential for Hedgehog (HH) signaling and can be targeted to suppress HH-driven medulloblastoma
Chang-Chih Wu, Shirui Hou, Brent A. Orr, Yong Ha Youn, Fanny Roth, Charles G. Eberhart, Young-Goo Han
bioRxiv 130872; doi: https://doi.org/10.1101/130872
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