New Results
Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly
Tatsiana Aneichyk, William.T. Hendriks, Rachita Yadav, David Shin, Dadi Gao, Christine A. Vaine, Ryan L. Collins, Alexei Stortchevoi, Benjamin Currall, Harrison Brand, Carrie Hanscom, Caroline Antolik, Marisela Dy, Ashok Ragavendran, Patrick Acuña, Criscely Go, Yechiam Sapir, Brian J. Wainger, Daniel Henderson, Jyotsna Dhakal, Naoto Ito, Neil Weisenfeld, David Jaffe, Nutan Sharma, Xandra O. Breakefield, Laurie J. Ozelius, D. Cristopher Bragg, Michael E. Talkowski
doi: https://doi.org/10.1101/149872
Tatsiana Aneichyk
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
3Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, 02142, USA;
William.T. Hendriks
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
Rachita Yadav
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
3Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, 02142, USA;
David Shin
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
Dadi Gao
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
3Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, 02142, USA;
Christine A. Vaine
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
Ryan L. Collins
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
3Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, 02142, USA;
6Program in Bioinformatics and Integrative Genomics, Division of Medical Sciences, Harvard Medical School, Boston, MA, 02115, USA;
Alexei Stortchevoi
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Benjamin Currall
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Harrison Brand
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Carrie Hanscom
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Caroline Antolik
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Marisela Dy
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
Ashok Ragavendran
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Patrick Acuña
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
Criscely Go
7Jose Reyes Memorial Medical Center, Manila, 1003, Philippines;
Yechiam Sapir
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Brian J. Wainger
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
Daniel Henderson
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
Jyotsna Dhakal
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
Naoto Ito
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
Neil Weisenfeld
8Genome Sequencing and Analysis Program, Broad Institute, Cambridge, MA, 02142, USA;
David Jaffe
8Genome Sequencing and Analysis Program, Broad Institute, Cambridge, MA, 02142, USA;
Nutan Sharma
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
Xandra O. Breakefield
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
9Department of Radiology, Massachusetts General Hospital, Boston, MA, 02114, USA;
Laurie J. Ozelius
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
D. Cristopher Bragg
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
5Harvard Brain Science Initiative, Harvard Medical School, Cambridge, MA, 02138, USA;
Michael E. Talkowski
1Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA;
2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA;
3Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, 02142, USA;
4The Collaborative Center for X-linked Dystonia Parkinsonism, Massachusetts General Hospital, Charlestown, MA, 02129, USA;
10Departments of Psychiatry and Pathology, Massachusetts General Hospital, Boston, MA, 02114, USA;
11Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, 02114, USA
Article usage
Posted June 14, 2017.
Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly
Tatsiana Aneichyk, William.T. Hendriks, Rachita Yadav, David Shin, Dadi Gao, Christine A. Vaine, Ryan L. Collins, Alexei Stortchevoi, Benjamin Currall, Harrison Brand, Carrie Hanscom, Caroline Antolik, Marisela Dy, Ashok Ragavendran, Patrick Acuña, Criscely Go, Yechiam Sapir, Brian J. Wainger, Daniel Henderson, Jyotsna Dhakal, Naoto Ito, Neil Weisenfeld, David Jaffe, Nutan Sharma, Xandra O. Breakefield, Laurie J. Ozelius, D. Cristopher Bragg, Michael E. Talkowski
bioRxiv 149872; doi: https://doi.org/10.1101/149872
Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly
Tatsiana Aneichyk, William.T. Hendriks, Rachita Yadav, David Shin, Dadi Gao, Christine A. Vaine, Ryan L. Collins, Alexei Stortchevoi, Benjamin Currall, Harrison Brand, Carrie Hanscom, Caroline Antolik, Marisela Dy, Ashok Ragavendran, Patrick Acuña, Criscely Go, Yechiam Sapir, Brian J. Wainger, Daniel Henderson, Jyotsna Dhakal, Naoto Ito, Neil Weisenfeld, David Jaffe, Nutan Sharma, Xandra O. Breakefield, Laurie J. Ozelius, D. Cristopher Bragg, Michael E. Talkowski
bioRxiv 149872; doi: https://doi.org/10.1101/149872
Subject Area
Subject Areas
- Biochemistry (11773)
- Bioengineering (8764)
- Bioinformatics (29239)
- Biophysics (14995)
- Cancer Biology (12118)
- Cell Biology (17428)
- Clinical Trials (138)
- Developmental Biology (9432)
- Ecology (14194)
- Epidemiology (2067)
- Evolutionary Biology (18326)
- Genetics (12258)
- Genomics (16813)
- Immunology (11882)
- Microbiology (28122)
- Molecular Biology (11615)
- Neuroscience (61044)
- Paleontology (452)
- Pathology (1874)
- Pharmacology and Toxicology (3239)
- Physiology (4967)
- Plant Biology (10434)
- Synthetic Biology (2889)
- Systems Biology (7346)
- Zoology (1653)